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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60d2c52019a4dac84b8ca4b7eb1fecc15b02e70028bdca90d3e105d295de436f' 
  AND token = 'uiCbCroCO7ARDpvw5W8N9N5XflolyIYm17jSDM577SU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}