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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60cfca45a0727315c5d4849b044ba5a2d5de28a9a84810e9a6ad856767f27b29' 
  AND token = '6HD26zzqS5NrADaKQikLttXARSHav28zLLsKJESn5Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}