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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '649163266cdbc17459b5d5691aca91a69b0fefcaaf1d4381c453422c57c4cad5' 
  AND token = 'aPLni4/2JATsvHROoO3Usxo0wPe7C6NACif8Y9Po5tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}