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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66949c3ad95a6956de8f0790506c551596cc3c124cf1a8009f900eef50778ac' 
  AND token = 'Av1OpEGlWj/Mk1dtJJsKyEGZ6uYbCRtUuv7PiJps4cU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}