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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9341605c5c9df0a348189af9f6695826ae35a1e53e125dc63a4b184471ab2d78' 
  AND token = '5Po0BWD8z5qihjFqNXB3ZxY0Bwqoxcw8BZCm35azHsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}