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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '36bcbd22f16721c13d1e7f0e73c69dede712640907ed050b5cab493b42c57754' 
  AND token = 'STQp1cm69152BGCobwDkiVX/nJw3GvCEArhRD6F5GRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}