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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46ef63b975de59e2eb9faecab89466c466b9252b5e2bd1c37a476d2fce08d45c' 
  AND token = 'aP+WhFpD7nIRcpp59ArR47AysHsDVHril6tbDYu/mMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}