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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae88aba34e50b8c8c34e5642bd1d51b43b008438f44e0da8c0c4ebbedafd654' 
  AND token = 'ucLYAmAcQjMy/y2NFpuveb8UCj584gbWPfEiLMWtt+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}