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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1fdc41babbdc4ee55387f236bd9117bb179eb4c9ef470b6a20c387d0992bada' 
  AND token = 'Wx2G+co7IU/eH1krZyPfPZs+53VxSFRtWTVWOrsn3So=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}