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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f67ee60936d725cd8d1192cb08c29657696833d53cbde895cac959a1f68cd1e3' 
  AND token = 'n44TgFLWvTT8mbdEV+4AV9TLQHw3nbN163jsYUGYZRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}