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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f5e13f2717b4c770c5469f979ed848e928b0b5ff7cda72ceb5216dc2df9c2de' 
  AND token = 'qyxqiv/bi9M0RiV6m7aKnwqODT8gbaFTAg6d/f2KFls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}