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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a9b2b4f5fcc4250634594c623cbf48f1739b577437ca4befb4ffad1fc080bdf' 
  AND token = 'NzFSzssHJJHr7FjLdwCPs+7aazoVAEoXTIsP5sldUR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}