SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6d9abb750fe534fb04fccc4826cdb85c54daf0fe4804d006c9cfa8d71d280cd' 
  AND token = 'k452+BVoqBsmWPEc3z3UW8I67KPQfnDNnOplP5DavhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}