SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246d8e844d87ee30009637e15bd6695183dd78bd0db8d337888bb977ec3b9d9e' 
  AND token = '83Z3bY8jNQ3aQpuAdaGUSGvcKFZaTRs3UAUB7DLLks8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}