SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe280777bb96fedba31c3d66d91349ef3005e0d177b4dfe124bbedd79fd4827d' 
  AND token = '4GrHXurSLjsWIrhIeBhgtBOKG6zWs2tAeGSHntxiloo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}