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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db8506303737f55ce63d9f1f6c1fde1fa510c12091bcd933968f0ece231b380b' 
  AND token = '201fmQdGuEM7c2LQFN7m0Lyh0oZLKm9f6fYgPZr+Kl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}