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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '193f4473ea88e71641b6e4b29b05635e8afbc4fdcdd90a32135a7a5b9275e4d9' 
  AND token = 'nfgcXf+eP1r/JW1qanSEW0bMQmC8/0avNAPqsGg+6F8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}