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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b81f48dadd94ca63a631b7d63d3b93ff0e14a01e95e3f3a875743159d15196b' 
  AND token = 'JA996jmcTzDUn2jiIOynW6broXNiK1rck13WlqcBnJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}