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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ccf2da80e2172b17bf3e3e5e5848ee6c61c3dea183ffbce701fa665660ff221' 
  AND token = 'qi9jRBL0w/0NmlvEkCN9OzZ0Hylag2bfM/2h2qAERc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}