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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0c7ec5ef6bc7274c49711be1a53f4f8ea669a71c03898d91405b808ae9b6e27' 
  AND token = 'qf/RPxgMPDZxYrXAxH8+3XitQo7EVYm+BegUkgyoNVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}