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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21e288e062d5dc90fcaeb88e963d2f12fc3e1d286401d82d26ed5a49b8592e69' 
  AND token = 'aHIY7q3G+YQ1BQ2M2dSJ0b0Gtn5gMeXRUgZHjiISPU0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}