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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65aa1f7455ace2b0520b39455f82a09d48af775e7a46927ec1e4f59ff9660f63' 
  AND token = '0Rx93uVRUB4P5YGWtcD/XdKiPUmwmHQ3AKWLCIckLhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}