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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7bdbe0b1095e2648d3618966f73f2e62df4c08eb5db1ad19eb28a4aca0f69421' 
  AND token = '4zrqlXy31wzi8YShiBEveS7ryPMEstLeuqSiKQTZFPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}