SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ecf5907e8937c61bd2d01b42cb9fcae52f7f013f172052ecb41ecddb560543' 
  AND token = 'ov7NIF23SeckYKQDUBomnfyizidq6NdTtxFCqss5qd8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}