SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '335f8751c1b8a47b8ef7d61616eb9c08a38b6ba2ce42d4f562eb3f188f439e6b' 
  AND token = 'kiWku3dPbLzZfWtegb+OhEoo6eTg2IKmrIvOuUfLGRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}