SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '330310bba299aa247cd990514c317faa7c71820c259f8027917d68feaee693e6' 
  AND token = 'Cz5zEoS1DQZfVnRyb18VBTnVt04JoTHO/xC9mziXvMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}