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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebc01c256afbfe42ad1138849308d0f013a4e98469d6c99d85a719a42a231b17' 
  AND token = 'pLWPG5GvFW6nszG6rAIx0tuRfWG9qL2PTQOpPqOJk6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}