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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfb6d91cb03505c0d4e8a0ce20ad18738f1ce020cf5a7fb0d6137cac71e3e2af' 
  AND token = '+iPobotVBT2g9hhOfZ8pbWiKV9uZjw7TKos2N0MvlEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}