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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ff67a8e69e42f29d47e25988d48fc19b484acaae544e262b667963d9023d50f' 
  AND token = 'g+S+7x6D4FR9F/oplnvdl7r56dmUBrGgJHi83/IYkWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}