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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '73750a7d00996eac8640f438d519a3a2e4a3cda954481219a623a9422e28a533' 
  AND token = 'UCu3a5ro4g6Q1HDgAx3LcmfQgWZAwe16rELpggfQQUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}