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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cfbedeb68ed0b90b82790535e7e2950305486fd8748d25976a0f500b79a697d' 
  AND token = 'elMCbhUgnC6O7FS8+xH1zRdSDXzVm/pPxhHvjAb6ZtQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}