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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f908ead5e9a7a4df66375ce41e3c8796d6c6619527e476900d64f1edbf8f6f1' 
  AND token = 'whFa1i0EnmBRJMSUsoc7mSbnIExxY1IzRTAmUPp1sIk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}