SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c58c2096ad26e648871c710989a9c78fc8886c85e4f227dae256fd6d7fc0853' 
  AND token = 'f8GYcf9EhOGYhgX8GIFGS+f9VIQKKNzRwbsnhCS+f+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}