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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fbaebac63b172d305288b3f230dfc72e32d53326729e6e211becdc5daef9314' 
  AND token = 'nOsMi5rYhI1+H1Gu8/Qyh+1AiXuEIbGhsLR4sIco25c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}