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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f72fb9aebbff04615de2027b02adf70d5b0af8025d8f4c141544e6012a55ba5' 
  AND token = 'C9XTwj1be8QMUyAo5zCanfXKd+eZHeNjMT0MGAQurs0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}