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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7872a683d703b4e352954818228e77bcf1cc72a99e2c164b2533304bea1f180' 
  AND token = 'yn0YYDclJ5Cj2+AyXe/WEZg8A38hgrHB2kWsbKuI5ek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}