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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '493b1b39441ad8fda563be60cf2589fb672e7148c7f816cd5ca34b96454acc12' 
  AND token = 'JWQ4uUJJDCtWrr2V4GDEzDsGLqH29elkiVfP2AdQWpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}