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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '428254ac13039b23b0946d9d91d4c363ac716ed710a48ff980c0ffc7a902ec95' 
  AND token = 'noPE5Y05EBux4tbUeqJDSdh2J5+oAa/BOlTMSCVe4GY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}