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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '226c32952d75f2289f38c558b42765a881ec6a34bc1bd50a76e5caa51599010c' 
  AND token = 'ZN/zpV8x7P87tN6GxCBXAxcX3kyTgKKEBVx9FxQ6kqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}