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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5bb404f1b9d57aa857a5bf7e5b56d7306bd133ee1964d5bcb5ea2af57078a3a2' 
  AND token = 'zZTf1OQ25u07KAP0mpoqIjPjRNtrnCeehzIbPAGY3Uc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}