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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b5bae60854b5312e39c11c9a643d9ceeac6e7b387983733d2c5383b7e674e2d' 
  AND token = 'm8FQ+4TcLBfurN0sagfFIk7qq9C3FVkUicDJp8azVSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}