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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25d81e0aa7ee5bc4672bd7ec47cdb1ed3cd6203b193c1245e30ad19890b23683' 
  AND token = '6OoYocOC9klLCCKat2psaeYLJFye+LEgfhPIr6Sg6kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}