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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782f2f12d2947fea4e35ea24efb1c5405f1df77ae5d855d66fa7a8de2f8d4a40' 
  AND token = 'GP2BpdZ/9MkDADsTfRS2AOYD3yBjys5u4xJdkvrACqA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}