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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf6a26cdfe3af14347a7678cc259af0a71f439e097b993f8b7a4d25f5782c9eb' 
  AND token = 'A7Ymu3N0WSXwvSk7V+nfYsMJchBW3LeaA/Mwl0EZslY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}