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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f0ed8af3094e7a7d7662bdd0d5f97785d22d3eab2da76327b26d953a0eb34b5' 
  AND token = 'd0qeNO3d3V25GuYEAZ643HdNAOSkpfUNnsnlxFD6zJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}