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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28082c0651806ef81be8d2663e05e7ad08bace914af5dd584e60f9d9e36dcb77' 
  AND token = 'R29Rd5DlLNdoWtdkMjxRKV5n7oOUXAgv1QQeN9E0Ses=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}