SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7dd864b3ca2d4e94e98e80a12a73c406a1e9a38eed5be75c456d6bcf5dea2c80' 
  AND token = 'gD6J8XsR5RSXj8fwcxbepwBOq5vDa8acZuvgc3Qnqeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}