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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64ed91320ee8b1b21ae5647309ad67e6d55acb585324b3922b36259b4d72e9d4' 
  AND token = '/VInaFYIVkW4LzA15jj0mSX4AOuislADH+YfjSjrjx8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}