SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d56c9427579ee2c8d85182f8da36d044009f3b6b4510fce4abe27db80c1da6f' 
  AND token = 'EqD5XHjl3FxvM91lKedbMKfkW9h0Ax+xQTv34B3f7Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}