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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81794a47cf29d819a6619235922c0a41843c04b67d96966f29d175ac5501f0b4' 
  AND token = 'MATEf6tNYKH8OiD7uQyfD8jKSD0i9v3YsRNaUUxRpaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}